Meaning: 'Little' means a small amount or degree, indicating that the success was minimal.

Wrong options:

• least: 'Least' is a superlative form that indicates the smallest amount among three or more, which does not fit here as we are discussing a general lack of success, not a comparison.
• transported: 'Transported' is a verb that does not fit grammatically in this context, as it does not describe the amount of success.
• amended: 'Amended' is a verb meaning to make changes or improvements, which does not relate to the context of success in easing pain.
• remained: 'Remained' is a verb that indicates a state of being, which does not fit as it does not describe the success of alcohol and opium.
• because of: 'Because of' is a prepositional phrase that indicates a reason, which does not fit grammatically or contextually here.
• there of: 'There of' is not a standard phrase in English and does not fit grammatically or contextually.

Correct answer: remained

Explanation: The word 'remained' is a verb that indicates the state of patients during operations. It fits grammatically as it follows the subject 'patients' and aligns with the context of discussing their consciousness during procedures.

Meaning: 'Remained' means to continue to be in a particular state, indicating that patients were still conscious.

Wrong options:

• little: 'Little' is an adjective that does not fit here as it does not describe a state of being or action.
• transported: 'Transported' is a verb that refers to moving something from one place to another, which does not fit the context of patients' consciousness.
• amended: 'Amended' is a verb meaning to change or improve, which does not relate to the state of patients during operations.
• there of: 'There of' is not a standard phrase in English and does not fit grammatically or contextually.
• because of: 'Because of' is a prepositional phrase that indicates a reason, which does not fit grammatically or contextually here.
• least: 'Least' is a superlative form that does not fit as it does not describe a state of being.

Correct answer: transported

Explanation: The word 'transported' is a verb that indicates the action of moving ether in heavy glass bottles. It fits grammatically as it describes what was done with ether and aligns with the context of discussing its handling.

Meaning: 'Transported' means to carry or move something from one place to another, indicating how ether was handled.

Wrong options:

• little: 'Little' is an adjective that does not fit here as it does not describe an action related to ether.
• amended: 'Amended' is a verb meaning to change or improve, which does not relate to the action of moving ether.
• remained: 'Remained' is a verb that indicates a state of being, which does not fit the context of discussing the action of transporting ether.
• there of: 'There of' is not a standard phrase in English and does not fit grammatically or contextually.
• because of: 'Because of' is a prepositional phrase that indicates a reason, which does not fit grammatically or contextually here.
• least: 'Least' is a superlative form that does not fit as it does not describe an action.

Correct answer: because of

Explanation: The phrase 'because of' is a prepositional phrase that indicates the reason for the potential danger associated with chloroform. It fits grammatically as it introduces a cause-and-effect relationship and aligns with the context of discussing the risks involved.

Meaning: 'Because of' means due to or on account of, indicating the reason for the effects on the heart.

Wrong options:

• little: 'Little' is an adjective that does not fit here as it does not indicate a reason or cause.
• transported: 'Transported' is a verb that does not fit grammatically or contextually as it does not relate to the cause of the effects on the heart.
• amended: 'Amended' is a verb meaning to change or improve, which does not relate to the context of discussing reasons for danger.
• remained: 'Remained' is a verb that indicates a state of being, which does not fit the context of discussing reasons for effects.
• there of: 'There of' is not a standard phrase in English and does not fit grammatically or contextually.
• least: 'Least' is a superlative form that does not fit as it does not indicate a reason.